Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332874 | 0.76 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL31332871 | 0.76 | MEN1 (0.33) | FDPSMEN1KMT2A | |
| SCHEMBL13722210 | 0.74 | DGAT1 (0.40) | FDPS | |
| SCHEMBL9810639 | 0.73 | — | — | |
| SCHEMBL20011271 | 0.71 | FDPS (0.44) | FDPSKMT2AADORA2BALDH1A1 | |
| SCHEMBL31332883 | 0.70 | ALDH1A1 (0.43) | KMT2AALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL19611492 | 0.70 | FDPS (0.47) | FDPSADORA2BALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL16479467 | 0.70 | FDPS (0.43) | FDPSALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL20011449 | 0.70 | POLB (0.50) | FDPSMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL19848132 | 0.69 | MEN1 (0.46) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |