Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535179 | 0.83 | MTNR1A (0.40) | MTNR1AMTNR1BTP53TSHRDRD2 | |
| SCHEMBL5892013 | 0.83 | KDM4E (0.35) | MEN1KMT2ATSHR | |
| SCHEMBL10715567 | 0.83 | FAAH (0.48) | MEN1KMT2A | |
| SCHEMBL5891996 | 0.80 | POLB (0.34) | MTNR1ADRD2 | |
| SCHEMBL26980870 | 0.77 | CNR1 (0.55) | MEN1KMT2A | |
| SCHEMBL28141626 | 0.77 | KMT2A (0.32) | MEN1KMT2A | |
| SCHEMBL11643386 | 0.76 | ALDH1A1 (0.37) | TSHR | |
| SCHEMBL29563222 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL7509232 | 0.71 | KMT2A (0.45) | MTNR1AMTNR1BMEN1KMT2ATP53 | |
| SCHEMBL598305 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137416-A | 2-Acylamidoethyl-2-imidazolines | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |