⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532915 | 0.93 | CTSL (0.36) | — | |
| SCHEMBL11538385 | 0.89 | OPRM1 (0.34) | — | |
| SCHEMBL6284322 | 0.79 | CTSL (0.38) | — | |
| SCHEMBL6284323 | 0.79 | CTSL (0.36) | — | |
| SCHEMBL11534663 | 0.77 | — | — | |
| SCHEMBL11431711 | 0.74 | — | — | |
| SCHEMBL11422642 | 0.74 | — | — | |
| SCHEMBL11426667 | 0.74 | — | — | |
| SCHEMBL11414454 | 0.74 | — | — | |
| SCHEMBL11534353 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |