Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532915 | 0.91 | CTSL (0.36) | OPRM1OPRK1OPRD1CARM1PRMT6 | |
| SCHEMBL11534784 | 0.89 | — | — | |
| SCHEMBL6284322 | 0.77 | CTSL (0.38) | OPRM1 | |
| SCHEMBL6284323 | 0.77 | CTSL (0.36) | OPRM1 | |
| SCHEMBL11532289 | 0.73 | CYP3A4 (0.31) | — | |
| SCHEMBL11422482 | 0.73 | LMNA (0.31) | OPRM1OPRK1OPRD1 | |
| SCHEMBL11529992 | 0.72 | — | — | |
| SCHEMBL11415205 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL11540619 | 0.72 | — | — | |
| SCHEMBL11421898 | 0.72 | LMNA (0.30) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |