Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533870 | 0.83 | ALDH1A1 (0.41) | NPC1RAB9AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11535816 | 0.80 | ALDH1A1 (0.38) | MAPTL3MBTL1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL11537092 | 0.75 | BCHE (0.39) | GAA | |
| SCHEMBL11533627 | 0.73 | — | — | |
| SCHEMBL11057664 | 0.71 | GAA (0.49) | NPC1RAB9AALDH1A1KMT2AP2RX7 | |
| SCHEMBL11532371 | 0.70 | TSHR (0.34) | ALDH1A1GAA | |
| SCHEMBL11531728 | 0.70 | GAA (0.36) | NPC1RAB9AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11173720 | 0.70 | — | — | |
| SCHEMBL11620440 | 0.70 | PRKCA (0.38) | KMT2ALMNA | |
| SCHEMBL11469385 | 0.70 | TAS1R3 (0.44) | NPC1RAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |