Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17509716 | 0.85 | MAOA (0.47) | ALDH1A1MAPK1TSHRTDP1CYP3A4 | |
| SCHEMBL13995711 | 0.85 | ALDH1A1 (0.48) | ALDH1A1MAPK1TSHRTDP1CYP3A4 | |
| SCHEMBL20495651 | 0.84 | KMT2A (0.51) | ALDH1A1MAPK1TSHRTDP1CYP3A4 | |
| SCHEMBL30945860 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPK1TSHRTDP1CYP3A4 | |
| SCHEMBL25479303 | 0.79 | LMNA (0.57) | ALDH1A1MAPK1L3MBTL1CA2KMT2A | |
| SCHEMBL2932638 | 0.79 | CA12 (0.58) | ALDH1A1MAPK1TSHRTDP1CYP3A4 | |
| SCHEMBL11531874 | 0.79 | NPSR1 (0.43) | ALDH1A1MAPK1L3MBTL1CA2KMT2A | |
| SCHEMBL1038338 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPK1TSHRTDP1CYP3A4 | |
| SCHEMBL12659603 | 0.78 | CHRM2 (0.53) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL2936645 | 0.76 | CA12 (0.55) | ALDH1A1MAPK1TSHRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157343-A | Preparation of aromatic diamines | UOP INC. (US) | 1979-06-05 | — | — | US | disclosed |