Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.67 |
| ▸ | GSR | P00390 | 7/20 | 0.63 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 3/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.58 |
| ▸ | HBB | P68871 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | PRNP | P04156 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15061348 | 0.97 | ADORA2A (0.72) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL20091298 | 0.94 | MBNL1 (0.71) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163842 | 0.93 | MBNL1 (0.70) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163843 | 0.93 | MBNL1 (0.70) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163922 | 0.93 | MBNL1 (0.70) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163888 | 0.93 | MBNL1 (0.70) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163885 | 0.93 | MBNL1 (0.70) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL18163883 | 0.93 | MBNL1 (0.70) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL7869225 | 0.92 | MBNL1 (0.81) | MBNL1MEN1KMT2ATDP1ADORA2A | |
| SCHEMBL20087027 | 0.91 | MBNL1 (0.80) | MBNL1MEN1KMT2ATDP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289024-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2013-10-31 | — | — | US | disclosed |
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | ZALICUS INC. | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | FLNA, FLNB, PIGS | MBNL1 2302/4885MEN1 3612/4885KMT2A 3886/4885 |
| US-20130289024-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | FLNA, FLNB, PIGS | MBNL1 2302/4885MEN1 3612/4885KMT2A 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.