Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532132 | 0.91 | DGKA (0.43) | DGKAEPHX2DNM1NAAA | |
| SCHEMBL11532213 | 0.86 | DGKA (0.42) | DGKAEPHX2DNM1PRSS1PRSS2 | |
| SCHEMBL11533027 | 0.84 | CHRM1 (0.30) | — | |
| SCHEMBL11530792 | 0.81 | NAAA (0.39) | DGKAEPHX2NAAA | |
| SCHEMBL11439112 | 0.79 | NAAA (0.38) | NAAAMEN1KMT2A | |
| SCHEMBL11591436 | 0.76 | DGKA (0.44) | DGKAEPHX2DNM1NAAAPRSS1 | |
| SCHEMBL11591615 | 0.76 | DGKA (0.44) | DGKAEPHX2DNM1NAAAPRSS1 | |
| SCHEMBL11666975 | 0.75 | PRKCA (0.34) | NAAA | |
| SCHEMBL11535520 | 0.75 | NAAA (0.43) | DGKANAAALMNA | |
| SCHEMBL11535623 | 0.75 | CHRM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |