Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1812607 | 0.81 | LPAR1 (0.40) | MEN1KMT2ALPAR1SMN1; SMN2MAPT | |
| SCHEMBL7960240 | 0.81 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL7949836 | 0.81 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL7960904 | 0.81 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL7961786 | 0.79 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL16463001 | 0.78 | OPRM1 (0.36) | MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL4501238 | 0.78 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8704918 | 0.76 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL7964417 | 0.76 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL8703008 | 0.76 | LPAR1 (0.45) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | FISCHER REINER | 2011-04-21 | — | — | US | disclosed |
| US-7888285-B2 | 2,4,6-phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-02-15 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | MEN1 4847/4885KMT2A 321/4885LPAR1 2667/4885 |
| US-20110092368-A1 | 2,4,6-Phenyl-substituted cyclic ketoenols | CYP4X1, KDM4E, PDHX | MEN1 4855/4885KMT2A 276/4885LPAR1 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.