SCHEMBL11535250

SCHEMBL11535250

NC1CCCCc2sccc21

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
KEAP1 Q14145 1/20 0.41
CYP19A1 P11511 1/20 0.37
TBXAS1 P24557 1/20 0.37
DRD3 P35462 1/20 0.37
USP2 O75604 1/20 0.36
GID4 Q8IVV7 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
NOS2 P35228 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11542466 0.98 LMNA (0.46) LMNAADRA2AADRA2BADRA2CKEAP1
SCHEMBL1266138 0.94 ADRA2A (0.46) LMNAADRA2AADRA2BADRA2CKEAP1
SCHEMBL14578646 0.94 ADRA2A (0.46) LMNAADRA2AADRA2BADRA2CKEAP1
SCHEMBL14578645 0.94 ADRA2A (0.46) LMNAADRA2AADRA2BADRA2CKEAP1
Hydrochloric Acid SCHEMBL6775379 0.92 ADRA2A (0.45) LMNAADRA2AADRA2BADRA2CKEAP1
SCHEMBL14914794 0.85
SCHEMBL14916238 0.85
SCHEMBL6648853 0.85
SCHEMBL19674159 0.77 KEAP1 (0.47) LMNAADRA2AADRA2BADRA2CKEAP1
SCHEMBL18723891 0.76 LMNA (0.46) LMNAADRA2AADRA2BADRA2CKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150035-A ANIMAL CROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1979-04-17 US claimed
US-4153611-A ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1979-05-08 US disclosed
US-4150035-A ANIMAL CROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1979-04-17 US disclosed
US-4150035-A ANIMAL CROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1979-04-17 US disclosed