Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540235 | 0.86 | ALDH1A3 (0.43) | ALDH1A3ALDH1A1CYP2A6KMT2ALMNA | |
| SCHEMBL11538324 | 0.83 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1CYP2A6KMT2ALMNA | |
| SCHEMBL6833277 | 0.82 | LMNA (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2DRD1 | |
| SCHEMBL869828 | 0.80 | FFAR1 (0.43) | KMT2ALMNAMAPT | |
| Propionic Acid SCHEMBL17748851 | 0.76 | FFAR1 (0.43) | ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL5272949 | 0.74 | ALDH1A1 (0.52) | ALDH1A3ALDH1A1CYP2A6KMT2ALMNA | |
| SCHEMBL997736 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A3ALDH1A1CYP2A6KMT2ASMN1; SMN2 | |
| SCHEMBL11485968 | 0.71 | ALDH1A1 (0.46) | ALDH1A3ALDH1A1CYP2A6KMT2ALMNA | |
| SCHEMBL9470287 | 0.70 | ALDH1A3 (0.52) | ALDH1A3ALDH1A1CYP2A6KMT2ALMNA | |
| SCHEMBL1695379 | 0.70 | ALDH1A3 (0.51) | ALDH1A3ALDH1A1CYP2A6KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163859-A | ANTILIPEMIC, FUNGICIDES, BACTERICIDES | G. D. SEARLE & CO. (US) | 1979-08-07 | — | — | US | disclosed |