Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535311 | 0.95 | TDP1 (0.49) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL11532136 | 0.95 | TDP1 (0.55) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL11532390 | 0.92 | CA12 (0.58) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL11531289 | 0.90 | NAAA (0.53) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL11534635 | 0.89 | SMN1; SMN2 (0.55) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL27782025 | 0.88 | HRH1 (0.54) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL4341122 | 0.84 | LMNA (0.57) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| SCHEMBL11769016 | 0.83 | CYP1A2 (0.54) | TDP1SMN1; SMN2CYP1A2CA12CA1 | |
| Ethylene Glycol SCHEMBL11535314 | 0.81 | SMN1; SMN2 (0.57) | TDP1SMN1; SMN2CYP1A2CYP2C19HRH1 | |
| Ethylene Glycol SCHEMBL11532139 | 0.81 | SMN1; SMN2 (0.57) | TDP1SMN1; SMN2CYP1A2CYP2C19HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153795-A | Cobalt pyridyl catalysts for hydroformylation | DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1979-05-08 | — | — | US | disclosed |