Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531974 | 0.90 | CYP19A1 (0.42) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11536284 | 0.87 | LMNA (0.37) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11539190 | 0.87 | TSHR (0.54) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11532830 | 0.87 | LMNA (0.50) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11536119 | 0.85 | LMNA (0.41) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11536569 | 0.84 | TSHR (0.51) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11535387 | 0.83 | LMNA (0.44) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11532979 | 0.82 | TSHR (0.44) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11538722 | 0.82 | CYP19A1 (0.47) | TSHRLMNAMAPTCYP19A1HSP90AA1 | |
| SCHEMBL11535471 | 0.81 | TSHR (0.58) | TSHRLMNACYP19A1HSP90AA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |