Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533358 | 0.89 | CYP19A1 (0.43) | LMNACYP19A1ALDH1A1GAAHSP90AA1 | |
| SCHEMBL11535310 | 0.87 | TSHR (0.42) | LMNASMN1; SMN2CYP19A1ALDH1A1HSP90AA1 | |
| SCHEMBL11531901 | 0.87 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2CYP19A1ALDH1A1GAA | |
| SCHEMBL11534227 | 0.86 | LMNA (0.47) | LMNASMN1; SMN2CYP19A1ALDH1A1GAA | |
| SCHEMBL11531685 | 0.85 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2CYP19A1ALDH1A1GAA | |
| SCHEMBL11531850 | 0.84 | LMNA (0.39) | LMNASMN1; SMN2ALDH1A1GAAHSP90AA1 | |
| SCHEMBL11532826 | 0.84 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2ALDH1A1HSP90AA1TSHR | |
| SCHEMBL11534440 | 0.84 | LMNA (0.43) | LMNASMN1; SMN2CYP19A1ALDH1A1GAA | |
| SCHEMBL11533723 | 0.83 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2ALDH1A1GAATSHR | |
| SCHEMBL11530465 | 0.83 | ALDH1A1 (0.42) | LMNASMN1; SMN2CYP19A1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |