Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 10/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574702 | 0.79 | ADAMTS5 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL2138946 | 0.79 | ADAMTS5 (0.42) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL1404438 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2NPSR1ALDH1A1LMNAADAMTS5 | |
| SCHEMBL27738063 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL29289314 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL6079454 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL11598874 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL6691265 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 | |
| SCHEMBL5438948 | 0.72 | LMNA (0.57) | ALDH1A1LMNAMMP2MMP9MMP13 | |
| SCHEMBL11677504 | 0.72 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150234-A | WATER RESISTANT | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |
| US-4137139-A | WATER RESISTANT LAMINATES, ADHESIVES, COATINGS | CIBA-GEIGY CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |
| US-4071477-A | CASTING AND LAMINATING RESINS | CIBA-GEIGY CORPORATION (US) | 1978-01-31 | — | — | US | disclosed |