SCHEMBL6079454

SCHEMBL6079454

CC1(CCS)NC(=O)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 1/20 0.46
ADAMTS5 Q9UNA0 14/20 0.38
MMP2 P08253 5/20 0.38
ADAM17 P78536 5/20 0.38
ADAMTS4 O75173 1/20 0.38
MMP13 P45452 2/20 0.37
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29289314 1.00 SMN1; SMN2 (0.47) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL13209009 0.82 SMN1; SMN2 (0.42) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL1404438 0.80 SMN1; SMN2 (0.49) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL11598874 0.78 SMN1; SMN2 (0.47) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL27738063 0.78 SMN1; SMN2 (0.47) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL6691265 0.77 SMN1; SMN2 (0.46) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL9190800 0.75 SMN1; SMN2 (0.45) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL11677504 0.75 SMN1; SMN2 (0.45) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL11535348 0.75 SMN1; SMN2 (0.45) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2
SCHEMBL11676230 0.75 SMN1; SMN2 (0.45) SMN1; SMN2NPSR1ALDH1A1ADAMTS5MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050112729-A1 Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid AJINOMOTO CO., INC. (JP) 2005-05-26 US claimed
CN-106380433-B A kind of isolation and purification method of N acetyl D, L methionine 宁夏紫光天化蛋氨酸有限责任公司 2018-04-20 CN disclosed
CN-106380433-A Separation and purification method for N-acetyl-D, L-methionine 宁夏紫光天化蛋氨酸有限责任公司 2017-02-08 CN disclosed
US-20060210989-A1 Screening process for hydantoin racemases DEGUSSA AG (DE) 2006-09-21 US disclosed
US-20050112729-A1 Recombinant DNA having hydantoinase gene and carbamylase gene and process for producing amino acid AJINOMOTO CO., INC. (JP) 2005-05-26 US disclosed
EP-1493809-A1 RECOMBINANT DNA HAVING HYDANTOINASE GENE AND CARBAMYLASE GENE AND PROCESS FOR PRODUCING AMINO ACID Ajinomoto Co., Inc. (JP) 2005-01-05 EP disclosed
WO-2004111227-A2 SCREENING PROCESS FOR HYDANTOIN RACEMASES DEGUSSA AG (DE) 2004-12-23 WO disclosed
EP-0219034-A2 Process for the preparation of mesophilic microorganisms containing D-hydantoinase active at a higher temperature BASF Aktiengesellschaft (DE) 1987-04-22 EP disclosed
EP-0046186-B1 METHOD OF PREPARING D-N-CARBAMOYL-ALPHA-AMINO ACIDS, AND MICROORGANISMS THEREFOR BASF Aktiengesellschaft (DE) 1984-05-02 EP disclosed
EP-0046186-A2 Method of preparing D-N-carbamoyl-alpha-amino acids, and microorganisms therefor BASF Aktiengesellschaft (DE) 1982-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060210989-A1 Screening process for hydantoin racemases HARS1, AARS1, HINT1 SMN1; SMN2 4769/4885NPSR1 681/4885ALDH1A1 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.