SCHEMBL1153537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21959555	0.92	ESR1 (0.67)	ESR1ESR2ALDH1A1LDHARAB9A
	SCHEMBL28067587	0.90	ALDH1A1 (0.57)	ESR1ESR2ALDH1A1LDHAPOLB
	SCHEMBL1153337	0.88	LDHA (0.59)	ESR1ESR2ALDH1A1LDHAPOLB
	SCHEMBL1154248	0.86	ALDH1A1 (0.53)	ESR1ESR2ALDH1A1LDHAPOLB
	SCHEMBL13243493	0.85	PPARG (0.57)	ESR1ESR2ALDH1A1LDHAKMT2A
	SCHEMBL1152868	0.82	FAAH (0.51)	ESR1ESR2ALDH1A1LDHAPOLB
	SCHEMBL18165316	0.82	ESR1 (0.61)	ESR1ESR2POLBKMT2AMEN1
	SCHEMBL18481327	0.82	ESR1 (0.61)	ESR1ESR2POLBKMT2AMEN1
	SCHEMBL27639581	0.81	LDHA (0.61)	ESR1ESR2LDHACYP1A2CYP2D6
	SCHEMBL13305527	0.80	ALDH1A1 (0.53)	ALDH1A1LDHAPOLBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.