Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451642 | 0.90 | BCHE (0.71) | BCHEGAAATMOPRK1SIGMAR1 | |
| SCHEMBL11096038 | 0.90 | BCHE (0.71) | BCHEGAAATMOPRK1SIGMAR1 | |
| SCHEMBL11816814 | 0.85 | BCHE (0.67) | BCHEGAAATMOPRK1SIGMAR1 | |
| SCHEMBL11815017 | 0.84 | OPRK1 (0.77) | BCHEGAAATMOPRK1SIGMAR1 | |
| SCHEMBL14731886 | 0.83 | TMEM97 (0.77) | BCHEKCNH2TMEM97KMT2AMEN1 | |
| SCHEMBL11824647 | 0.81 | BCHE (0.74) | BCHEGAAATMSIGMAR1KMT2A | |
| SCHEMBL28983267 | 0.80 | BCHE (0.60) | BCHEGAAATMOPRK1SIGMAR1 | |
| SCHEMBL14731718 | 0.79 | TMEM97 (0.74) | BCHEGAAATMSIGMAR1KCNH2 | |
| SCHEMBL9706053 | 0.78 | ADRB2 (0.66) | GAAOPRK1SIGMAR1KMT2AMEN1 | |
| SCHEMBL11463351 | 0.78 | ADRB2 (0.66) | GAAOPRK1SIGMAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140713-A | Phenylethanolamine therapeutic agents | ALLEN & HANBURYS LIMITED (GB) | 1979-02-20 | — | — | US | disclosed |