Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.83 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.75 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.75 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.75 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538836 | 0.91 | CYP19A1 (1.00) | CYP19A1SLC6A2SLC6A4SLC6A3AKT1 | |
| SCHEMBL733008 | 0.87 | SLC6A3 (1.00) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL673181 | 0.87 | CYP19A1 (0.59) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL3695767 | 0.87 | CYP19A1 (0.59) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| Ammonia Solution, Strong SCHEMBL5999715 | 0.84 | SLC6A3 (0.95) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL22388390 | 0.80 | CYP1A2 (0.64) | CYP19A1SLC6A2SLC6A4SLC6A3AKT1 | |
| SCHEMBL8176557 | 0.80 | CYP19A1 (0.85) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL14393365 | 0.79 | SLC6A2 (0.75) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL10038666 | 0.79 | SLC6A2 (0.75) | CYP19A1SLC6A2SLC6A4SLC6A3CFTR | |
| SCHEMBL6501455 | 0.78 | CYP19A1 (0.68) | CYP19A1SLC6A2SLC6A4SLC6A3AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180660-A | CONTAINING FORMYL SUBSTITUTED PYRROLE GROUP | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1979-12-25 | — | — | US | disclosed |
| US-4148998-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1979-04-10 | — | — | US | disclosed |
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-4122260-A | CONTAINING FORMYL SUBSTITUTED PYRROLE, ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1978-10-24 | — | — | US | disclosed |