Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 4/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 4/20 | 1.00 |
| ▸ | CFTR | P13569 | 1/20 | 0.62 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5999715 | 0.97 | SLC6A3 (0.95) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL29361168 | 0.88 | SLC6A2 (0.78) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL11535640 | 0.87 | CYP19A1 (0.83) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| Sulfuric Acid SCHEMBL11540575 | 0.87 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| Sulfuric Acid SCHEMBL11540571 | 0.87 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL10038666 | 0.87 | SLC6A2 (0.75) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL14393365 | 0.87 | SLC6A2 (0.75) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL11540603 | 0.83 | SLC6A3 (0.69) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| Hydrochloric Acid SCHEMBL28863932 | 0.82 | SLC6A2 (0.68) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| Hydrochloric Acid SCHEMBL28268728 | 0.82 | SLC6A2 (0.68) | SLC6A3SLC6A2SLC6A4CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| WO-2024042448-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF RUXOLITINIB | GRANULES INDIA LIMITED (IN) | 2024-02-29 | — | — | WO | claimed |
| EP-3985008-A1 | PROCESSES AND INTERMEDIATES FOR MAKING A JAK INHIBITOR | Incyte Holdings Corporation (US) | 2022-04-20 | — | — | EP | claimed |
| CN-111875607-B | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2021-12-03 | — | — | CN | claimed |
| US-20210253584-A1 | Processes for Preparing Jak Inhibitors and Related Intermediate Compounds | INCYTE HOLDINGS CORPORATION | 2021-08-19 | — | — | US | claimed |
| EP-3398952-B1 | SYNTHESIS PROCESS OF RUXOLITINIB | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-07-14 | — | — | EP | claimed |
| EP-3473625-B1 | PREPARATION METHOD FOR CHIRAL PYRROLOPYRIMIDINE COMPOUND | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2021-06-02 | — | — | EP | claimed |
| CN-111875607-A | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2020-11-03 | — | — | CN | claimed |
| US-10766901-B2 | Preparation method for chiral pyrrolopyrimidine compound | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-09-08 | — | — | US | claimed |
| CN-109311892-B | Preparation method of chiral pyrrolopyrimidine compound | 正大天晴药业集团股份有限公司 | 2020-09-04 | — | — | CN | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0474789-B1 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | GENETIC SYSTEMS CORP (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0788487-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | Novartis AG (CH) | 1997-08-13 | — | — | EP | claimed |
| WO-1996013489-A1 | PROCESS FOR THE PREPARATION OF TETRAZOLES | NOVARTIS AG (CH) | 1996-05-09 | — | — | WO | claimed |
| US-5439792-A | Synthesizing a cyclic viral protein epitope | GENETIC SYSTEMS CORPORATION (US) | 1995-08-08 | — | — | US | claimed |
| US-5360928-A | Synthesis and use of amino acid fluorides as peptide coupling reagents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-11-01 | — | — | US | claimed |
| EP-0474789-A4 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | — | 1992-06-03 | — | — | EP | claimed |
| EP-0474789-A1 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | GENETIC SYSTEMS CORPORATION (US) | 1992-03-18 | — | — | EP | claimed |
| WO-1990015071-A1 | CYSTEINE THIOL-PROTECTED PEPTIDES FOR USE IN IMMUNOASSAYS | GENETIC SYSTEMS CORPORATION (US) | 1990-12-13 | — | — | WO | claimed |
| US-4009087-A | N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE | M&T CHEMICALS INC. (US) | 1977-02-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253584-A1 | Processes for Preparing Jak Inhibitors and Related Intermediate Compounds | JAK3, JAK1, JAK2 | SLC6A3 4292/4885SLC6A2 4861/4885SLC6A4 4762/4885 |
| US-10766901-B2 | Preparation method for chiral pyrrolopyrimidine compound | DHPS, DPYD, MPHOSPH6 | SLC6A3 3549/4885SLC6A2 3200/4885SLC6A4 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.