Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528155 | 0.89 | PKM (0.57) | TAS1R3TAS1R1PKMMAPTGAA | |
| SCHEMBL11531276 | 0.84 | SLC2A1 (0.43) | TAS1R3TAS1R1PKMMAPTL3MBTL1 | |
| SCHEMBL11528466 | 0.83 | NPC1 (0.46) | TAS1R3TAS1R1GAAL3MBTL1KDM4E | |
| SCHEMBL11528710 | 0.83 | NPC1 (0.43) | TAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL21730504 | 0.82 | MAPT (0.46) | TAS1R3TAS1R1PKMMAPTGAA | |
| SCHEMBL16521818 | 0.81 | PKM (0.48) | TAS1R3TAS1R1PKMMAPTGAA | |
| SCHEMBL11527219 | 0.81 | NPC1 (0.45) | NPC1RAB9A | |
| SCHEMBL11528010 | 0.81 | PKM (0.50) | TAS1R3TAS1R1PKMMAPTGAA | |
| SCHEMBL11529335 | 0.80 | L3MBTL1 (0.60) | TAS1R3TAS1R1PKMMAPTGAA | |
| SCHEMBL26545301 | 0.79 | ALDH1A1 (0.43) | TAS1R3TAS1R1MAPTL3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161474-A | STABILIZERS, ANTIOZONANTS FOR VULCANIZABLE DIENE RUBBERS | MONSANTO COMPANY (US) | 1979-07-17 | — | — | US | disclosed |