Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536912 | 0.85 | LMNA (0.61) | ATMHPGDCXCR4TSHRPOLB | |
| SCHEMBL11537697 | 0.84 | ATM (0.61) | ATMCXCR4POLBUSP2HTT | |
| SCHEMBL11541000 | 0.83 | CNR1 (0.48) | ATMHPGDTSHRCNR1CNR2 | |
| SCHEMBL11535652 | 0.82 | CXCR4 (0.60) | ATMHPGDCXCR4TSHRPOLB | |
| SCHEMBL11536229 | 0.81 | CXCR4 (0.53) | ATMCXCR4POLBSMN1; SMN2USP2 | |
| SCHEMBL11537128 | 0.81 | ATM (0.57) | ATMHPGDCXCR4POLBUSP2 | |
| SCHEMBL11536219 | 0.80 | CXCR4 (0.64) | ATMCXCR4POLBSMN1; SMN2HTT | |
| SCHEMBL11538782 | 0.80 | LMNA (0.62) | ATMCXCR4POLBUSP2MEN1 | |
| SCHEMBL11536601 | 0.80 | CXCR4 (0.54) | ATMCXCR4POLBUSP2KDM4E | |
| SCHEMBL11539718 | 0.79 | ALDH1A1 (0.64) | ATMHPGDCXCR4POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |