Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537128 | 0.87 | ATM (0.57) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11536912 | 0.84 | LMNA (0.61) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11538782 | 0.84 | LMNA (0.62) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11536046 | 0.84 | MMP13 (0.61) | ATMLMNAHTTUSP2APEX1 | |
| SCHEMBL11535832 | 0.84 | ATM (0.59) | ATMPOLBCXCR4LMNAMEN1 | |
| SCHEMBL11538732 | 0.80 | POLB (0.64) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11536229 | 0.80 | CXCR4 (0.53) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11535652 | 0.79 | CXCR4 (0.60) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11536601 | 0.79 | CXCR4 (0.54) | ATMPOLBCXCR4LMNAGAA | |
| SCHEMBL11535238 | 0.79 | TSHR (0.56) | ATMLMNAGAAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |