Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536417 | 0.95 | KMT2A (0.38) | ALDH1A1KMT2AMAPTCYP1A2CYP2C19 | |
| SCHEMBL11534109 | 0.94 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EPKML3MBTL1 | |
| SCHEMBL11538505 | 0.89 | GABRA1 (0.40) | ALDH1A1KMT2AKDM4EPKMMAPT | |
| SCHEMBL11536777 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KDM4EPKMMAPTRXFP1 | |
| SCHEMBL11536526 | 0.88 | KMT2A (0.41) | ALDH1A1KMT2AKDM4EPKML3MBTL1 | |
| SCHEMBL11534104 | 0.88 | MAPT (0.36) | ALDH1A1KDM4EPKML3MBTL1MAPT | |
| SCHEMBL11535434 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EPKML3MBTL1 | |
| SCHEMBL11537930 | 0.86 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTRXFP1CYP1A2 | |
| SCHEMBL11534846 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPTRXFP1SMN1; SMN2 | |
| SCHEMBL11542791 | 0.84 | MEN1 (0.39) | ALDH1A1KMT2AKDM4EPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139625-A | 5-(Substituted triphenylmethyl)picolinamides and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |
| US-4133887-A | Trityl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4127662-A | ANTIACNE | SCHERING CORPORATION (US) | 1978-11-28 | — | — | US | disclosed |
| US-4123433-A | ANTIACNE AGENTS | SCHERING CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4044140-A | Trityl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |