Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.49 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543374 | 0.81 | TDP1 (0.53) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL741950 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL3002573 | 0.80 | TDP1 (0.68) | SMN1; SMN2LMNATDP1TSHRHTT | |
| SCHEMBL19911315 | 0.79 | TDP1 (0.50) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL1024585 | 0.77 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL11543707 | 0.75 | SLC9A1 (0.50) | SMN1; SMN2LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2640498 | 0.74 | TDP1 (0.63) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL28299452 | 0.74 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL501944 | 0.72 | SMN1; SMN2 (0.85) | SMN1; SMN2LMNATDP1TSHRALOX15 | |
| SCHEMBL5374402 | 0.72 | SMN1; SMN2 (0.85) | SMN1; SMN2LMNATDP1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177155-A | N-AMINOMETHYL-TRIAZOLES AND IMIDAZOLES FOR MAKING ANTIFREEZES NONCORROSIVE | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |