SCHEMBL1153650

SCHEMBL1153650

C=CC(=O)OC(Br)(Br)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 4/20 0.42
TSHR P16473 1/20 0.42
AKT1 P31749 1/20 0.41
HTT P42858 1/20 0.40
TGM2 P21980 2/20 0.37
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 2/20 0.37
KCNN4 O15554 1/20 0.37
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 3/20 0.35
CYP2D6 P10635 1/20 0.35
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CES1 P23141 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7859075 0.84 HTT (0.46) THRBALDH1A1TSHRAKT1HTT
SCHEMBL4596471 0.83 ALDH1A1 (0.48) THRBALDH1A1TSHRAKT1HTT
SCHEMBL438661 0.82 THRB (0.43) THRBALDH1A1TSHRAKT1HTT
SCHEMBL22472203 0.82 THRB (0.43) THRBALDH1A1TSHRAKT1HTT
SCHEMBL29577536 0.82 THRB (0.43) THRBALDH1A1TSHRAKT1TGM2
Ethane SCHEMBL28624063 0.81 ALDH1A1 (0.47) THRBALDH1A1TSHRAKT1HTT
SCHEMBL28769396 0.81 KCNN4 (0.43) ALDH1A1TSHRHTTCYP2C19HIF1A
SCHEMBL16086568 0.81 THRB (0.42) THRBALDH1A1TSHRAKT1HTT
SCHEMBL3169549 0.81 CYP2C19 (0.46) THRBALDH1A1TSHRAKT1HTT
SCHEMBL27702244 0.81 THRB (0.42) THRBALDH1A1TSHRAKT1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119907872-A Three-dimensional ring material and use thereof 陶氏环球技术有限责任公司 2025-04-29 CN claimed
US-20110045285-A1 TRANSPARENT CONDUCTIVE FILM FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed
US-20060292450-A1 Non-aqueous electrolyte secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2006-12-28 US disclosed
US-4812032-A DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE TORAY INDUSTRIES, INC. (JP) 1989-03-14 US disclosed
US-4721377-A COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE TORAY INDUSTRIES, INC. (JP) 1988-01-26 US disclosed
EP-0176874-A2 A highly-refractive plastic lens TORAY INDUSTRIES, INC. (JP) 1986-04-09 EP disclosed
US-4369298-A Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1983-01-18 US disclosed