Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | CD38 | P28907 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | IDH2 | P48735 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539328 | 0.91 | MEN1 (0.83) | KMT2AMEN1CD38NPC1RAB9A | |
| SCHEMBL11535044 | 0.88 | MEN1 (0.78) | KMT2AMEN1CD38KDM4ENPC1 | |
| SCHEMBL11538908 | 0.87 | MEN1 (0.77) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL11541657 | 0.86 | MEN1 (0.76) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL11542433 | 0.86 | MEN1 (0.76) | KMT2AMEN1CD38NPC1RAB9A | |
| SCHEMBL11538930 | 0.86 | MEN1 (0.76) | KMT2AMEN1CD38NPC1RAB9A | |
| SCHEMBL11537220 | 0.86 | MEN1 (0.76) | KMT2AMEN1CD38KDRL3MBTL1 | |
| SCHEMBL11538746 | 0.84 | MEN1 (0.72) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL11472293 | 0.83 | MEN1 (0.71) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11537785 | 0.83 | MEN1 (0.71) | KMT2AMEN1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |