Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | CD38 | P28907 | 2/20 | 0.57 |
| ▸ | IDH2 | P48735 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539010 | 0.88 | KMT2A (0.67) | MEN1KMT2ACD38IDH2TAAR1 | |
| SCHEMBL11541657 | 0.86 | MEN1 (0.76) | MEN1KMT2AIDH2TAAR1RAB9A | |
| SCHEMBL11537220 | 0.86 | MEN1 (0.76) | MEN1KMT2ACD38IDH2CYP3A4 | |
| SCHEMBL11536552 | 0.86 | KMT2A (1.00) | MEN1KMT2ACD38IDH2RAB9A | |
| SCHEMBL11535043 | 0.85 | IDH2 (0.72) | MEN1KMT2AIDH2RAB9AMAPT | |
| SCHEMBL11540163 | 0.85 | MEN1 (0.60) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11542433 | 0.84 | MEN1 (0.76) | MEN1KMT2ACD38IDH2RAB9A | |
| SCHEMBL11472293 | 0.83 | MEN1 (0.71) | MEN1KMT2AIDH2RAB9AMAPT | |
| SCHEMBL11537785 | 0.83 | MEN1 (0.71) | MEN1KMT2ARAB9AMAPTNPC1 | |
| SCHEMBL11538530 | 0.83 | MEN1 (0.71) | MEN1KMT2AIDH2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |