Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CD38 | P28907 | 1/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536552 | 0.91 | KMT2A (1.00) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11535044 | 0.90 | MEN1 (0.78) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11538908 | 0.87 | MEN1 (0.77) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11542433 | 0.86 | MEN1 (0.76) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11541657 | 0.86 | MEN1 (0.76) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11538746 | 0.84 | MEN1 (0.72) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11472293 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11539010 | 0.82 | KMT2A (0.67) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL11538807 | 0.82 | KMT2A (0.67) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL11537127 | 0.82 | MEN1 (0.67) | MEN1KMT2AALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160097-A | INTERMEDIATES FOR FUNGICIDAL AND ANTIINFLAMMATORY 4-SUBSTITUTED IMIDAZO(1,2-A)QUINOXALINES | WESTWIND PHARMACEUTICALS, INC. (US) | 1979-07-03 | — | — | US | claimed |