Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442654 | 0.89 | MEN1 (0.47) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL3476351 | 0.84 | MAPT (0.65) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL3719812 | 0.78 | KDM4E (0.54) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL4828036 | 0.77 | KDM4E (0.50) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL12230334 | 0.76 | MAPT (0.55) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL2949227 | 0.76 | LMNA (0.58) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL30561536 | 0.76 | MAOA (0.57) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL1083820 | 0.76 | MAOA (0.57) | MAPTKDM4ELMNAALDH1A1TSHR | |
| SCHEMBL11543450 | 0.74 | L3MBTL1 (0.47) | HRH3GABRA1GABRG2GABRB3 | |
| SCHEMBL30225649 | 0.74 | MEN1 (0.50) | MAPTKDM4ELMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178293-A | Isoindolinyl derivatives | ZOECON CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |