Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534949 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL7276461 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL15559032 | 0.75 | CA1 (0.51) | KDM4EALDH1A1GAASMN1; SMN2CYP2C9 | |
| SCHEMBL9754384 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL4074628 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL11537082 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL31191409 | 0.70 | CA1 (0.63) | KDM4EALDH1A1SMN1; SMN2CYP2C9MCL1 | |
| SCHEMBL353738 | 0.70 | CA1 (0.63) | KDM4EALDH1A1SMN1; SMN2CYP2C9MCL1 | |
| SCHEMBL25148779 | 0.70 | KDM4E (0.55) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL4429820 | 0.70 | KDM4E (0.93) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137408-A | BACTERICIDES, ANTIBIOTICS | WARNER-LAMBERT (US) | 1979-01-30 | — | — | US | disclosed |
| US-4137408-A | BACTERICIDES, ANTIBIOTICS | WARNER-LAMBERT (US) | 1979-01-30 | — | — | US | disclosed |
| US-4101661-A | PENICILLINS, CEPHALOSPORINS | WARNER-LAMBERT (US) | 1978-07-18 | — | — | US | disclosed |
| US-4101661-A | PENICILLINS, CEPHALOSPORINS | WARNER-LAMBERT (US) | 1978-07-18 | — | — | US | disclosed |