Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593327 | 0.84 | ALDH1A1 (0.33) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL8374363 | 0.83 | SLC6A4 (0.37) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL11239172 | 0.83 | MAOA (0.34) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL11242024 | 0.83 | SLC6A4 (0.33) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL7877014 | 0.82 | SLC6A4 (0.41) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL27430431 | 0.82 | TSHR (0.43) | MAOAMAOBICMTTSHRMAPK1 | |
| SCHEMBL11234154 | 0.80 | SLC6A4 (0.35) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL28011963 | 0.79 | MAOA (0.36) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL11240325 | 0.77 | SLC6A4 (0.33) | SLC6A4SLC6A3MAOAMAOBKDM1A | |
| SCHEMBL11246022 | 0.77 | SLC6A4 (0.34) | SLC6A4SLC6A3ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154731-A | ANTISECRETORY AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-05-15 | — | — | US | disclosed |
| US-4105670-A | ANTISECRETORY, ANTIINFLAMMATORY, ANALGESIC, DECARBOXYLATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-08-08 | — | — | US | disclosed |