Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239172 | 0.89 | MAOA (0.34) | MAOAMAOBKDM1AUTS2RSLC6A4 | |
| SCHEMBL117206 | 0.85 | MAOA (0.38) | MAOAMAOBKDM1AUTS2RSLC6A4 | |
| SCHEMBL11234154 | 0.83 | SLC6A4 (0.35) | MAOAMAOBKDM1AUTS2RSLC6A4 | |
| SCHEMBL11240325 | 0.83 | SLC6A4 (0.33) | MAOAMAOBKDM1AUTS2RSLC6A4 | |
| SCHEMBL28011998 | 0.81 | EGFR (0.40) | MAOAMAOBSLC6A4SLC6A3LMNA | |
| SCHEMBL7877014 | 0.81 | SLC6A4 (0.41) | MAOAMAOBKDM1ASLC6A4SLC6A3 | |
| SCHEMBL7390254 | 0.81 | L3MBTL1 (0.45) | MAOAMAOBALDH1A1TSHRMAPK1 | |
| SCHEMBL10849609 | 0.80 | ALDH1A1 (0.38) | MAOAMAOBKDM1AUTS2RSLC6A4 | |
| SCHEMBL1593327 | 0.80 | ALDH1A1 (0.33) | MAOAMAOBKDM1AUTS2RSLC6A4 | |
| Phosphine SCHEMBL9482786 | 0.79 | L3MBTL1 (0.44) | MAOAMAOBALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102480956-B | Pyrido [4,3-b] indoles and methods of use | MEDIVATION TECHNOLOGIES INC | 2015-04-08 | — | — | CN | disclosed |