Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540169 | 0.91 | LTA4H (0.43) | LTA4HMCHR1KDM4EALDH1A1FGFR1 | |
| SCHEMBL11536484 | 0.90 | KDM4E (0.45) | LTA4HMCHR1KDM4EALDH1A1FGFR1 | |
| SCHEMBL11535981 | 0.81 | FGFR1 (0.49) | LTA4HMCHR1KDM4EALDH1A1FGFR1 | |
| Hydrochloric Acid SCHEMBL11532587 | 0.81 | FGFR1 (0.48) | LTA4HMCHR1KDM4EALDH1A1FGFR1 | |
| SCHEMBL31613810 | 0.77 | EGFR (0.50) | KMT2AMEN1KDM4C | |
| SCHEMBL5667766 | 0.77 | EGFR (0.50) | KMT2AMEN1KDM4C | |
| SCHEMBL11535586 | 0.77 | LTA4H (0.45) | LTA4HMCHR1KDM4EALDH1A1FGFR1 | |
| SCHEMBL11536152 | 0.76 | FGFR1 (0.48) | KDM4EALDH1A1FGFR1SRC | |
| SCHEMBL13489152 | 0.75 | EGFR (0.49) | KMT2AMEN1KDM4C | |
| SCHEMBL11881432 | 0.74 | LTA4H (0.57) | LTA4HKDM4ELMNAHTR6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |