Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535981 | 0.93 | FGFR1 (0.49) | LTA4HKDM4EALDH1A1FGFR1CHRNB2 | |
| Hydrochloric Acid SCHEMBL11532587 | 0.92 | FGFR1 (0.48) | LTA4HKDM4EALDH1A1FGFR1CHRNB2 | |
| SCHEMBL11536152 | 0.87 | FGFR1 (0.48) | KDM4EALDH1A1FGFR1CHEK1AURKA | |
| SCHEMBL11536267 | 0.82 | HTR7 (0.47) | LTA4HKDM4EALDH1A1FGFR1CHEK1 | |
| SCHEMBL11532756 | 0.81 | LTA4H (0.43) | LTA4HKDM4EALDH1A1FGFR1CHRNB2 | |
| SCHEMBL11536895 | 0.81 | HTR7 (0.46) | LTA4HKDM4EALDH1A1FGFR1CHEK1 | |
| SCHEMBL11537019 | 0.77 | LTA4H (0.47) | LTA4HKDM4EALDH1A1FGFR1CHRNB2 | |
| SCHEMBL11540169 | 0.75 | LTA4H (0.43) | LTA4HKDM4EALDH1A1FGFR1CHRNB2 | |
| SCHEMBL11536942 | 0.74 | HRH3 (0.53) | LTA4HFGFR1CHEK1AURKADAPK3 | |
| SCHEMBL6904077 | 0.74 | CHEK1 (0.65) | FGFR1CHEK1AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |