Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856197 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL11851612 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL11851151 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL11846240 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL11848921 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL11843788 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL11857637 | 0.92 | CASP2 (0.62) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL14197499 | 0.86 | PAOX (0.48) | PAOXCASP2KDM4EMAPK1HIF1A | |
| SCHEMBL48873 | 0.84 | — | — | |
| SCHEMBL29597675 | 0.83 | EPHX1 (0.63) | PAOXCASP2KDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015107170-A1 | NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE | ALPHABETA AB (SE) | 2015-07-23 | — | — | WO | disclosed |
| US-20100233104-A1 | Amino-Acid Functional Siloxanes, Methods Of Preparation and Applications | DOW CORNING LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| EP-1063982-B1 | ANTAGONISTS FOR TREATMENT OF CD11/CD18 ADHESION RECEPTOR MEDIATED DISORDERS | GENENTECH INC (US) | 2007-02-14 | — | — | EP | disclosed |
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233104-A1 | Amino-Acid Functional Siloxanes, Methods Of Preparation and Applications | DAO, AADAT, BCAT2 | PAOX 373/4885CASP2 4187/4885KDM4E 1308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.