Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534076 | 0.78 | CHRNA7 (0.39) | GRIN2BHPGDMEN1KMT2AMAPT | |
| SCHEMBL1433609 | 0.77 | SCN1A (0.41) | HPGDALOX15MEN1KMT2AMAPT | |
| SCHEMBL11534823 | 0.77 | GAA (0.44) | MEN1KMT2AGAA | |
| SCHEMBL11531728 | 0.76 | GAA (0.36) | GRIN2BALOX15MEN1KMT2AMAPT | |
| SCHEMBL4490161 | 0.75 | MAPK1 (0.36) | POLBALDH1A1GAAMAPK1 | |
| SCHEMBL11531807 | 0.74 | GAA (0.41) | MEN1KMT2AGAA | |
| SCHEMBL11529903 | 0.72 | HDAC3 (0.37) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL9869396 | 0.72 | TSHR (0.50) | GRIN2BHPGDALOX15MEN1KMT2A | |
| SCHEMBL11536246 | 0.72 | THRA (0.53) | LMNASMN1; SMN2 | |
| SCHEMBL11538893 | 0.71 | RAB9A (0.39) | MEN1KMT2AMAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |