Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317622 | 0.85 | GABRA1 (0.70) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11686986 | 0.83 | PTAFR (0.47) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11683606 | 0.82 | OPRK1 (0.53) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11716522 | 0.81 | OPRK1 (0.53) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11378371 | 0.81 | OPRK1 (0.56) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11385248 | 0.80 | OPRK1 (0.73) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL10404510 | 0.80 | CYP3A4 (0.56) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11863031 | 0.80 | OPRK1 (0.55) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11620744 | 0.80 | OPRK1 (0.60) | OPRK1GABRA1GABRA5GABRA2HPGD | |
| SCHEMBL11854548 | 0.78 | OPRK1 (0.47) | OPRK1GABRA1GABRA5GABRA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141902-A | SEDATIVES, TRANQUILIZERS, MUSCLE RELAXANTS | THE UPJOHN COMPANY (US) | 1979-02-27 | — | — | US | disclosed |