Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533907 | 0.79 | — | — | |
| SCHEMBL11472690 | 0.79 | GAA (0.34) | KMT2AMEN1GAAPKMHTT | |
| SCHEMBL11530540 | 0.78 | KMT2A (0.41) | KMT2AMEN1GAAMAOBMAOA | |
| SCHEMBL11468936 | 0.78 | GAA (0.32) | KMT2AMEN1GAAPKMHTT | |
| SCHEMBL11530668 | 0.78 | MAOB (0.36) | KMT2AMEN1GAAMAOBMAOA | |
| SCHEMBL994414 | 0.78 | KMT2A (0.47) | KMT2AMEN1GAAMAOBMAOA | |
| SCHEMBL11533442 | 0.77 | NAAA (0.34) | — | |
| SCHEMBL2834466 | 0.76 | NAAA (0.36) | — | |
| SCHEMBL14125250 | 0.76 | MAOB (0.32) | KMT2AMEN1GAAMAOBMAOA | |
| SCHEMBL11769042 | 0.74 | GAA (0.55) | KMT2AMEN1GAAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |