Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530674 | 0.85 | CACNA1A (0.33) | KCNH2 | |
| SCHEMBL11536214 | 0.82 | ABCB1 (0.38) | ALDH1A1LMNASMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL11533372 | 0.81 | SCN1A (0.43) | GAALMNASMN1; SMN2KCNH2 | |
| SCHEMBL11535558 | 0.80 | TSHR (0.42) | GAAKMT2AKCNH2 | |
| SCHEMBL11537693 | 0.78 | KMT2A (0.43) | MAOBMAOAGAAHTTALDH1A1 | |
| SCHEMBL6453784 | 0.78 | GAA (0.48) | MAOBMAOAGAAHTTALDH1A1 | |
| SCHEMBL11533448 | 0.77 | THRB (0.37) | GAAMEN1KMT2AKCNH2 | |
| SCHEMBL2958675 | 0.76 | ALOX5 (0.44) | MAOBMAOAGAAHTTALDH1A1 | |
| SCHEMBL11532899 | 0.76 | GAA (0.41) | GAAMEN1KMT2AKCNH2 | |
| SCHEMBL11536074 | 0.75 | BCHE (0.39) | GAAMEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |