Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543858 | 0.89 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL11537345 | 0.85 | DRD4 (0.56) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Benzoic Acid SCHEMBL11543852 | 0.83 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL11540608 | 0.83 | ADRB2 (0.55) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL11543042 | 0.83 | HTR1A (0.62) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL11541108 | 0.82 | ADRB2 (0.51) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Benzoic Acid SCHEMBL11538250 | 0.81 | HTR1A (0.57) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL11375285 | 0.80 | ADRB2 (0.49) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| SCHEMBL11537855 | 0.80 | ADRB2 (0.52) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Mindodilol SCHEMBL6295415 | 0.78 | ADRB2 (0.61) | ADRB2ADRB1ADRB3HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |