Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946331 | 0.80 | KMT2A (0.41) | KDM4ELMNACYP2C19KMT2AADRA2A | |
| SCHEMBL30492670 | 0.78 | BUB1 (0.40) | KMT2AHTR2AALDH1A1 | |
| SCHEMBL7185718 | 0.78 | BUB1 (0.40) | KMT2AHTR2AALDH1A1 | |
| SCHEMBL11529778 | 0.77 | KMT2A (0.44) | KDM4ELMNAKMT2AADRA2AADRA2B | |
| SCHEMBL29448021 | 0.77 | KMT2A (0.44) | KDM4ELMNAKMT2AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL9519799 | 0.76 | HTR2A (0.50) | KMT2AHTR2AALDH1A1 | |
| SCHEMBL24677864 | 0.76 | DRD2 (0.37) | KDM4ELMNACYP2C19KMT2AADRA2A | |
| SCHEMBL23966212 | 0.76 | BRD4 (0.52) | KDM4ELMNACYP2C19KMT2AADRA2A | |
| SCHEMBL11529130 | 0.76 | KMT2A (0.42) | KDM4ELMNACYP2C19KMT2AADRA1B | |
| SCHEMBL11532437 | 0.76 | LMNA (0.38) | KDM4ELMNACYP2C19KMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286231-B1 | CATALYST COMPOSITION COMPRISING FLUORIDED SUPPORT AND PROCESSES FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-10-09 | — | — | EP | disclosed |
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |