Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418047 | 0.77 | CYP11B2 (0.38) | DRD2DRD3CYP2C19KMT2ATSHR | |
| SCHEMBL11537869 | 0.76 | KDM4E (0.44) | CYP2C19KMT2AKDM4ELMNATSHR | |
| SCHEMBL23811488 | 0.74 | DRD2 (0.33) | DRD2DRD3AVPR1A | |
| SCHEMBL26428055 | 0.71 | PDK2 (0.35) | DRD2DRD3DPP8DPP9AVPR1A | |
| SCHEMBL23386192 | 0.71 | DRD2 (0.31) | DRD2DRD3AVPR1A | |
| SCHEMBL24375384 | 0.70 | DRD2 (0.33) | DRD2DRD3AVPR1A | |
| SCHEMBL30646089 | 0.70 | GRIN1 (0.41) | DRD2DRD3LMNAAVPR1AGRIN1 | |
| SCHEMBL24112694 | 0.70 | NAMPT (0.32) | DRD2DRD3KMT2A | |
| SCHEMBL21142646 | 0.69 | BRD4 (0.56) | CYP2C19CYP1A2KDM4ELMNADPP8 | |
| SCHEMBL21708059 | 0.69 | CNR2 (0.38) | DRD2DRD3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188819-A1 | SOS1 PROTEOLYSIS MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-09-15 | — | — | WO | disclosed |