Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 15/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538148 | 1.00 | CA1 (0.36) | CA1CA2FBP1ALDH1A1 | |
| SCHEMBL11540389 | 0.88 | KDM4E (0.40) | ALDH1A1 | |
| SCHEMBL11540386 | 0.88 | KDM4E (0.40) | ALDH1A1 | |
| SCHEMBL11540509 | 0.82 | CNR1 (0.35) | CA1CA2FBP1ALDH1A1 | |
| SCHEMBL11540515 | 0.82 | CNR1 (0.35) | CA1CA2FBP1ALDH1A1 | |
| SCHEMBL11539944 | 0.81 | ALDH1A1 (0.42) | CA1CA2ALDH1A1 | |
| SCHEMBL11539948 | 0.81 | ALDH1A1 (0.42) | CA1CA2ALDH1A1 | |
| SCHEMBL11537232 | 0.73 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL11537228 | 0.73 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL11538501 | 0.73 | KDM4E (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |