Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540509 | 1.00 | CNR1 (0.35) | CNR1F10ALDH1A1MAPTPTGES2 | |
| SCHEMBL11540386 | 0.89 | KDM4E (0.40) | ALDH1A1MAPK1KDM4ETDP1PKM | |
| SCHEMBL11540389 | 0.89 | KDM4E (0.40) | ALDH1A1MAPK1KDM4ETDP1PKM | |
| SCHEMBL11539948 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTPTGES2NPC1RAB9A | |
| SCHEMBL11539944 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTPTGES2NPC1RAB9A | |
| SCHEMBL11538148 | 0.82 | CA1 (0.36) | ALDH1A1FBP1CA1CA2 | |
| SCHEMBL11538151 | 0.82 | CA1 (0.36) | ALDH1A1FBP1CA1CA2 | |
| SCHEMBL11539361 | 0.81 | PTGES2 (0.38) | CNR1ALDH1A1MAPTPTGES2FBP1 | |
| SCHEMBL11539364 | 0.81 | PTGES2 (0.38) | CNR1ALDH1A1MAPTPTGES2FBP1 | |
| SCHEMBL11538501 | 0.74 | KDM4E (0.40) | ALDH1A1MAPTMAPK1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |