Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540447 | 0.89 | POLB (0.45) | NPSR1POLBMAPTLMNAMEN1 | |
| SCHEMBL11540274 | 0.88 | NPSR1 (0.47) | NPSR1MAPTKMT2AHTTKDM4E | |
| SCHEMBL11538126 | 0.86 | MAPT (0.58) | NPSR1POLBMAPTLMNAEDNRA | |
| SCHEMBL11540070 | 0.86 | NPSR1 (0.46) | NPSR1MAPTLMNAKMT2AHTT | |
| SCHEMBL11542615 | 0.86 | NPSR1 (0.46) | NPSR1MEN1KMT2AHTT | |
| SCHEMBL11541055 | 0.86 | NPSR1 (0.46) | NPSR1POLBMAPTLMNAMEN1 | |
| SCHEMBL11542917 | 0.84 | POLB (0.51) | NPSR1POLBMAPTBACE1MEN1 | |
| SCHEMBL11539823 | 0.83 | BACE1 (0.49) | NPSR1MAPTBACE1MEN1KMT2A | |
| SCHEMBL11540561 | 0.81 | TSHR (0.45) | MEN1KMT2AHTT | |
| SCHEMBL11544557 | 0.80 | MAPT (0.59) | NPSR1POLBMAPTLMNAEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | claimed |
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | disclosed |