Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | MLNR | O43193 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | GHSR | Q92847 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11538250 | 0.86 | HTR1A (0.57) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL11543042 | 0.85 | HTR1A (0.62) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL11544386 | 0.82 | HTR1A (0.47) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL11543858 | 0.78 | ADRB2 (0.53) | HTR1AADRB2ADRB1ADRB3MAPT | |
| SCHEMBL6295417 | 0.78 | ADRB2 (0.49) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL11541108 | 0.77 | ADRB2 (0.51) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL11539450 | 0.76 | ADRB2 (0.47) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| SCHEMBL11540608 | 0.76 | ADRB2 (0.55) | HTR1AADRB2ADRB1ADRB3MAPT | |
| SCHEMBL11595936 | 0.76 | HTR1A (0.67) | HTR1AADRB2ADRB1ADRB3SLC6A4 | |
| Benzoic Acid SCHEMBL11543852 | 0.76 | ADRB2 (0.53) | HTR1AADRB2ADRB1ADRB3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146630-A | HYPOTENSIVE AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1979-03-27 | — | — | US | disclosed |