Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4480437 | 0.85 | JAK2 (0.49) | GAASMN1; SMN2 | |
| SCHEMBL13538763 | 0.84 | SMN1; SMN2 (0.46) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL9052963 | 0.84 | TACR3 (0.43) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL15352654 | 0.84 | TACR3 (0.43) | L3MBTL1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL21193740 | 0.84 | SMN1; SMN2 (0.52) | L3MBTL1MEN1KMT2ACYP2C19NPC1 | |
| SCHEMBL11680904 | 0.82 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL11680901 | 0.82 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL21405164 | 0.82 | TMEM97 (0.49) | L3MBTL1MEN1KMT2ACYP2C19NPC1 | |
| SCHEMBL4364361 | 0.81 | GAA (0.41) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL9721933 | 0.80 | TSHR (0.48) | L3MBTL1MEN1KMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150136-A | ANTIDEPRESSANTS, ANALGESICS | SANDOZ LTD. (CH) | 1979-04-17 | — | — | US | disclosed |
| US-4081543-A | ANTIAGRESSIVE, CENTRAL NERVOUS SYSTEM DEPRESSANTS | SANDOZ LTD. (CH) | 1978-03-28 | — | — | US | disclosed |
| US-4034095-A | ANTIDEPRESSANT, ANTICHOLINERGIC | SANDOZ LTD. (CH) | 1977-07-05 | — | — | US | disclosed |
| US-4024265-A | ANTIDEPRESSANTS | SANDOZ LTD. (CH) | 1977-05-17 | — | — | US | disclosed |