Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680904 | 1.00 | L3MBTL1 (0.45) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL11538529 | 0.82 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL13711175 | 0.78 | GAA (0.37) | L3MBTL1TSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL30262299 | 0.76 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL18301302 | 0.76 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL18301301 | 0.76 | ALDH1A1 (0.40) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL8300960 | 0.75 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL14500775 | 0.75 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2797469 | 0.74 | GRM5 (0.55) | L3MBTL1MEN1KMT2ATSHRGAA | |
| SCHEMBL8539224 | 0.74 | MEN1 (0.47) | L3MBTL1MEN1KMT2ACYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4034095-A | ANTIDEPRESSANT, ANTICHOLINERGIC | SANDOZ LTD. (CH) | 1977-07-05 | — | — | US | disclosed |
| US-4024265-A | ANTIDEPRESSANTS | SANDOZ LTD. (CH) | 1977-05-17 | — | — | US | disclosed |