Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538753 | 1.00 | MAPT (0.49) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11543148 | 0.87 | MAPT (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11543151 | 0.87 | MAPT (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11539725 | 0.84 | NPSR1 (0.55) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL11539728 | 0.84 | NPSR1 (0.55) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL11540672 | 0.84 | KDM4E (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11540675 | 0.84 | KDM4E (0.41) | MAPTKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11540587 | 0.81 | NOTUM (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11539391 | 0.81 | NOTUM (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8027812 | 0.81 | KDM4E (0.43) | MAPTKDM4EALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | claimed |
| US-4169097-A | GASTRIC ANTISECRETORY AGENTS | MORTON-NORWICH PRODUCTS, INC. (US) | 1979-09-25 | — | — | US | disclosed |